Qwen 2.5 VL (72B) has 72 billion parameters. At standard 4-bit quantization with 8K context, it needs roughly 50.2 GB of VRAM — weights plus cache and runtime overhead.

VRAM by quantization

PrecisionWeightsCache/BufferTotal VRAM
2-bit (IQ2_XXS)23.0 GB8.6 GB33.7 GB
4-bit (Q4_K_M)39.6 GB8.6 GB50.2 GB
8-bit (Q8_0)75.6 GB8.6 GB86.2 GB
16-bit (FP16)144.0 GB8.6 GB154.6 GB

Which GPU can run Qwen 2.5 VL (72B) (at 4-bit)?

GPU classVRAMQwen 2.5 VL (72B) (50.2 GB)
8 GB · RTX 5060 / 40608 GBWon’t fit
12 GB · RTX 5070 / 306012 GBWon’t fit
16 GB · RTX 5070 Ti / 408016 GBWon’t fit
24 GB · RTX 4090 / 309024 GBWon’t fit
32 GB · RTX 509032 GBWon’t fit
48 GB · 2×24 / RTX 6000 Ada48 GBWon’t fit
128 GB · M-series / RTX Spark128 GBFits

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VRAM figures are reproducible estimates (weights + KV cache + overhead) and vary by runtime and quant format. Data current as of 2026-06-15.